Publikationen

2022

Terheyden-Keighley D, Leibinger M, Zeitler C and Fischer D (2022)
Transneuronal delivery of cytokines to stimulate mammalian spinal cord regeneration
Methods in Molecular Biology (in press)

Prokosch V, Liu H, Leibinger M and Fischer D (2022)
Regeneration of the optic nerve- how far are we from reality?
Ophthalmologe. 2022 May 2. doi: 10.1007/s00347-022-01628-0. Online ahead of print.

Terheyden-Keighley D, Hilla AM and Fischer D (2022)
CXCR4 signaling in CNS Regeneration: Friend or Foe?
Neural Regeneration Research; 17(7):1481-1483

Pryymachuk, G.; El-Awaad, E.; Piekarek, N.; Drebber, U.; Maul, A. C.; Hescheler, J.; Wodarz, A.; Pfitzer, G.; Neiss, W. F.; Pietsch, M.; Schroeter, M. M. Angiotensin II type 1 receptor localizes at the blood-bile barrier in humans and pigs. Histochem. Cell Biol. 2022, 157, 513-524

Hauser, S.; Sommerfeld, P.; Wodtke, J.; Hauser, C.; Schlitterlau, P.; Pietzsch, J.; Löser, R.; Pietsch, M.; Wodtke, R.Application of a fluorescence anisotropy-based assay to quantify transglutaminase 2 activity in cell lysates. Int. J. Mol. Sci. 2022, 23:4475

Despang, P., Salamon, S., Breitenkamp, A., Kuzmenkina, E., & Matthes, J. (2022). Inhibitory effects on L- and N-type calcium channels by a novel CaVβ1 variant identified in a patient with autism spectrum disorder. Naunyn-Schmiedeberg's archives of pharmacology395(4), 459–470. doi.org/10.1007/s00210-022-02213-7

Büsker, S., Jäger, W., Poschner, S., Mayr, L., Al Jalali, V., Gojo, J., Azizi, A. A., Ullah, S., Bilal, M., El Tabei, L., Fuhr, U., & Peyrl, A. (2022). Pharmacokinetics of metronomic temozolomide in cerebrospinal fluid of children with malignant central nervous system tumors. Cancer chemotherapy and pharmacology89(5), 617–627. doi.org/10.1007/s00280-022-04424-4

Rüdesheim, S., Selzer, D., Fuhr, U., Schwab, M., & Lehr, T. (2022). Physiologically-based pharmacokinetic modeling of dextromethorphan to investigate interindividual variability within CYP2D6 activity score groups. CPT: pharmacometrics & systems pharmacology11(4), 494–511. doi.org/10.1002/psp4.12776

Gründemann, D., Hartmann, L., & Flögel, S. (2022). The ergothioneine transporter (ETT): substrates and locations, an inventory. FEBS letters596(10), 1252–1269. doi.org/10.1002/1873-3468.14269

Grievink, H., Shamni, O., Krajewski, S., Steczek, Ł., Gründemann, D., Mishani, E., & Abourbeh, G. (2022). Organic Cation Transporter-Mediated Accumulation of Quinolinium Salts in the LV Myocardium of Rodents. Molecular imaging and biology, 10.1007/s11307-022-01728-y. Advance online publication. doi.org/10.1007/s11307-022-01728-y

Müller, J. P., & Gründemann, D. (2022). Does Intracellular Metabolism Render Gemcitabine Uptake Undetectable in Mass Spectrometry?. International journal of molecular sciences23(9), 4690. doi.org/10.3390/ijms23094690

Schmitz, K., Turnwald, E. M., Kretschmer, T., Janoschek, R., Bae-Gartz, I., Voßbrecher, K., Kammerer, M. D., Köninger, A., Gellhaus, A., Handwerk, M., Wohlfarth, M., Gründemann, D., Hucklenbruch-Rother, E., Dötsch, J., & Appel, S. (2022). Metformin Prevents Key Mechanisms of Obesity-Related Complications in Visceral White Adipose Tissue of Obese Pregnant Mice. Nutrients14(11), 2288. doi.org/10.3390/nu14112288

2021

CXCR4/CXCL12 mediated entrapment of axons at the injury site compromises optic nerve regeneration
Hilla AM, Baehr A, Leibinger M, Andreadaki A and Fischer D (2021)
PNAS; 118(21):e2016409118. doi: 10.1073/pnas.2016409118

Dose-dependent immunomodulatory effects of Bortezomib In Experimental Autoimmune Neuritis
Klimas R, Sgodzai M, Motte, Mohamad N, Renk P, Blusch A, Grüter T, Pedreiturria X, Gobrecht P, Fischer D, Schneider-Gold C, Reinacher-Schick A, Tannapfel A, Yoon MS, Gold R, Pitarokoili K (2021)
Brain Comm; 3(4):fcab238

Transneuronal delivery of designer cytokines: Perspectives for spinal cord injury
Terheyden-Keighley D, Leibinger M and Fischer D (2021)
Neural Regeneration Research; 17(2):338-340

Transneuronal delivery of hyper-IL-6 enables functional recovery after severe spinal cord injury in mice
Leibinger M, Zeitler C, Gobrecht P, Gisselmann G, Andreadaki A and Fischer D (2021)
Nature Comm; 12(1):391. doi: 10.1038/s41467-020-20112-4

ID: 492969
2-Substituted thienotetrahydropyridine derivatives: Allosteric ectonucleotidase inhibitors.
Arch Pharm (Weinheim) 2021; 354(12): ; Impact Factor=n.a.; Impact Factor 2020=3.751; Typ=Journal Article;
Schäkel L, Mirza S, Pietsch M, Lee SY, Keuler T, Sylvester K, Pelletier J, Sévigny J, Pillaiyar T, Namasivayam V, Gütschow M, Müller CE
Medline-ID vorhanden, Web of Science-ID (ISI-LOC) vorhanden

ID: 488922
Evaluation of body-surface-area adjusted dosing of high-dose methotrexate by population pharmacokinetics in a large cohort of cancer patients.
BMC Cancer 2021; 21(1): ; Impact Factor=n.a.; Impact Factor 2020=4.43; Typ=Journal Article;
Arshad UTaubert M, Seeger-Nukpezah T, Ullah S, Spindeldreier KC, Jaehde U, Hallek M, Fuhr U, Vehreschild JJ, Jakob C
Medline-ID vorhanden, Web of Science-ID (ISI-LOC) vorhanden

ID: 492977
Hyperosmolarity stimulates transporter-mediated insertion of estrone sulfate into the plasma membrane, but inhibits the uptake by SLC10A1 (NTCP).
Biochem Pharmacol 2021; 186(): ; Impact Factor=n.a.; Impact Factor 2020=5.858; Typ=Journal Article;
Müller JPKeufgens LGründemann D
Medline-ID vorhanden, Web of Science-ID (ISI-LOC) vorhanden

ID: 492976
Population pharmacokinetics and probability of target attainment in patients with sepsis under renal replacement therapy receiving continuous infusion of meropenem: Sustained low-efficiency dialysis and continuous veno-venous haemodialysis.
Br J Clin Pharmacol 2021; 87(11): 4293-4303; Impact Factor=n.a.; Impact Factor 2020=4.335; Typ=Journal Article;Research Support, Non-U.S. Gov't;
Westermann I, Gastine S, Müller C, Rudolph W, Peters F, Bloos F, Pletz M, Hagel S
Medline-ID vorhanden, Web of Science-ID (ISI-LOC) vorhanden

ID: 491400
Developing a Nationwide Infrastructure for Therapeutic Drug Monitoring of Targeted Oral Anticancer Drugs: The ON-TARGET Study Protocol.
Cancers (Basel) 2021; 13(24): ; Impact Factor=n.a.; Impact Factor 2020=6.639; Typ=Journal Article;
Mc Laughlin AM, Schmulenson E, Teplytska O, Zimmermann S, Opitz P, Groenland SL, Huitema ADR, Steeghs N, Müller L, Fuxius S, Illerhaus G, Joerger M, Mayer F, Fuhr U, Holdenrieder S, Hempel G, Scherf-Clavel O, Jaehde U, Kloft C, For The On-Target Study Consortium
Medline-ID vorhanden, Web of Science-ID (ISI-LOC) vorhanden

ID: 491401
Clinical Pharmacokinetics and Pharmacodynamics of Cefiderocol.
Clin Pharmacokinet 2021; 60(12): 1495-1508; Impact Factor=n.a.; Impact Factor 2020=6.447; Typ=Journal Article;Research Support, Non-U.S. Gov't;Review;
Bilal MEl Tabei LBüsker SKrauss CFuhr UTaubert M
Medline-ID vorhanden, Web of Science-ID (ISI-LOC) vorhanden

ID: 471447
A Model-Based Approach to Assess Unstable Creatinine Clearance in Critically Ill Patients.
Clin Pharmacol Ther 2021; 110(5): 1240-1249; Impact Factor=n.a.; Impact Factor 2020=6.875; Typ=Journal Article;
Ullah S, Zoller M, Jaehde U, Huseyn-Zada M, Weig T, Fuhr UArshad U, Zander J, Taubert M
Medline-ID vorhanden, Web of Science-ID (ISI-LOC) vorhanden

ID: 314447
Quantification of direct-acting oral anticoagulants: Application of a clinically validated liquid chromatography-tandem mass spectrometry method to forensic cases.
Drug Test Anal 2021; 13(2): 419-426; Impact Factor=n.a.; Impact Factor 2020=3.345; Typ=Journal Article;
Wiesen MHJFietz C, Jübner M, Iwersen-Bergmann S, Andresen-Streichert H, Müller C, Streichert T
Medline-ID vorhanden, Web of Science-ID (ISI-LOC) vorhanden

ID: 492982
Both Effects and Side Effects Must Be Taken Into Account.
Dtsch Arztebl Int 2021; 118(1-2): 11-11; Impact Factor=n.a.; Impact Factor 2020=5.594; Typ=Letter;Comment;
Matthes J
Medline-ID vorhanden, Web of Science-ID (ISI-LOC) vorhanden

ID: 492975
A model-based approach to describe creatinine kinetics in critically ill patients and its application in population pharmacokinetics
Eur J Clin Pharmacol 2021; 77 Suppl 1(SUPPL 1): 34-34; Impact Factor=n.a.; Impact Factor 2020=2.953; Typ=Meeting Abstract;
Ullah S, Zoller M, Jaehde U, Huseyn-Zada M, Weig T, Fuhr UArshad U, Zander J, Taubert M
Medline-ID fehlt, Web of Science-ID (ISI-LOC) vorhanden

ID: 491402
A preliminary population pharmacokinetic model for remdesivir and its metabolites based on published mean values from healthy subjects
Eur J Clin Pharmacol 2021; 77 Suppl 1(SUPPL 1): 4-5; Impact Factor=n.a.; Impact Factor 2020=2.953; Typ=Meeting Abstract;
Abouellil AFuhr UBilal M
Medline-ID fehlt, Web of Science-ID (ISI-LOC) vorhanden

ID: 488925
Evaluation of body surface area adjusted dosing of high-dose methotrexate by population pharmacokinetics in a large cohort of cancer patients
Eur J Clin Pharmacol 2021; 77 Suppl 1(SUPPL 1): 13-13; Impact Factor=n.a.; Impact Factor 2020=2.953; Typ=Meeting Abstract;
Arshad UTaubert MSeeger-Nukpezah TUllah SSpindeldreier KC, Jaehde U, Hallek MFuhr UVehreschild JJJakob C
Medline-ID fehlt, Web of Science-ID (ISI-LOC) vorhanden

ID: 492974
Pharmacokinetics of temozolomide in cerebrospinal fluid of children with malignant tumors - a pilot study
Eur J Clin Pharmacol 2021; 77 Suppl 1(SUPPL 1): 14-14; Impact Factor=n.a.; Impact Factor 2020=2.953; Typ=Meeting Abstract;
Buesker S, Peyrl A, al Jalali V, Jaeger W, Poschner S, Ullah SEl Tabei LFuhr U
Medline-ID fehlt, Web of Science-ID (ISI-LOC) vorhanden

ID: 492972
Rationale of a lower dexamethasone dose in prenatal congenital adrenal hyperplasia therapy based on pharmacokinetic modelling.
Eur J Endocrinol 2021; 185(3): 365-374; Impact Factor=n.a.; Impact Factor 2020=6.664; Typ=Journal Article;
Stachanow V, Neumann U, Blankenstein O, Fuhr U, Huisinga W, Michelet R, Reisch N, Kloft C
Medline-ID vorhanden, Web of Science-ID (ISI-LOC) vorhanden

ID: 467273
Advisory opinion of the AWMF Ad hoc Commission In-vitro Diagnostic Medical Devices regarding in-vitro diagnostic medical devices manufactured and used only within health institutions established in the Union according to Regulation (EU) 2017/746 (IVDR).
Ger Med Sci 2021; 19(): ; Impact Factor=n.a.; Impact Factor 2020=n.a.; Typ=Journal Article;
Hoffmüller P, Brüggemann M, Eggermann T, Ghoreschi K, Haase D, Hofmann J, Hunfeld KP, Koch K, Meisel C, Michl P, Müller J, Müller C, Rabenau HF, Reinhardt D, Riemenschneider MJ, Sachs UJ, Sack U, Stenzinger A, Streichert T, von Neuhoff N, Weichert W, Weinstock C, Zimmermann S, Spitzenberger F, AWMF Ad hoc Commision In-vitro Diagnostic Medical Devices
Medline-ID vorhanden, Web of Science-ID (ISI-LOC) fehlt

ID: 383678
Detection of systemic immunosuppressants in autologous serum eye drops (ASED) in patients with severe chronic ocular graft versus host disease.
Graefes Arch Clin Exp Ophthalmol 2021; 259(1): 121-128; Impact Factor=n.a.; Impact Factor 2020=3.117; Typ=Journal Article;
Tahmaz V, Wiesen MHJ, Gehlsen U, Sauerbier L, Stern ME, Holtick U, Gathof B, Scheid C, Müller C, Steven P
Medline-ID vorhanden, Web of Science-ID (ISI-LOC) vorhanden

ID: 492971
Rationale for a reduced dexamethasone dose in prenatal congenital adrenal hyperplasia therapy based on pharmacokinetic modelling
Horm Res Paediatr 2021; 94 Suppl 1(SUPPL 1): 384-384; Impact Factor=n.a.; Impact Factor 2020=2.852; Typ=Meeting Abstract;
Neumann U, Stachanow V, Blankenstein O, Fuhr U, Huisinga W, Reisch N, Kloft C
Medline-ID fehlt, Web of Science-ID (ISI-LOC) vorhanden

ID: 484719
Pharmacokinetics of remdesivir in a COVID-19 patient with end-stage renal disease on intermittent haemodialysis.
J Antimicrob Chemother 2021; 76(3): 825-827; Impact Factor=n.a.; Impact Factor 2020=5.79; Typ=Case Reports;Letter;Research Support, Non-U.S. Gov't;
Sörgel F, Malin JJ, Hagmann H, Kinzig M, Bilal M, Eichenauer DA, Scherf-Clavel O, Simonis A, El Tabei LFuhr U, Rybniker J
Medline-ID vorhanden, Web of Science-ID (ISI-LOC) vorhanden

ID: 491739
Plasma and soft tissue pharmacokinetics of ceftolozane/tazobactam in healthy volunteers after single and multiple intravenous infusion: a microdialysis study.
J Antimicrob Chemother 2021; 76(9): 2342-2351; Impact Factor=n.a.; Impact Factor 2020=5.79; Typ=Clinical Study;Journal Article;Research Support, Non-U.S. Gov't;
Al Jalali V, Wölfl-Duchek M, Taubert M, Matzneller P, Lackner E, Dorn C, Kratzer A, Wulkersdorfer B, Österreicher Z, Zeitlinger M
Medline-ID vorhanden, Web of Science-ID (ISI-LOC) vorhanden

ID: 383681
A New Homozygous CACNB2 Mutation has Functional Relevance and Supports a Role for Calcium Channels in Autism Spectrum Disorder.
J Autism Dev Disord 2021; 51(1): 377-381; Impact Factor=n.a.; Impact Factor 2020=4.291; Typ=Letter;
Graziano C, Despang P, Palombo F, Severi G, Posar A, Cassio A, Pippucci T, Isidori F, Matthes J, Bonora E
Medline-ID vorhanden, Web of Science-ID (ISI-LOC) vorhanden

ID: 486626
Depolarization induces nociceptor sensitization by CaV1.2-mediated PKA-II activation.
J Cell Biol 2021; 220(10): ; Impact Factor=n.a.; Impact Factor 2020=10.539; Typ=Journal Article;Research Support, Non-U.S. Gov't;
Isensee J, van Cann M, Despang P, Araldi D, Moeller K, Petersen J, Schmidtko A, Matthes J, Levine JD, Hucho T
Medline-ID vorhanden, Web of Science-ID (ISI-LOC) vorhanden

ID: 492981
A Population Pharmacokinetic Model of (R)- and (S-) Oxybutynin and Its Active Metabolites After Oral and Intravesical Administration to Healthy Volunteers.
J Clin Pharmacol 2021; 61(7): 961-971; Impact Factor=n.a.; Impact Factor 2020=3.126; Typ=Clinical Trial;Journal Article;Research Support, Non-U.S. Gov't;
Kretschmar MSuleiman AAKrause P, Albrecht U, Stein R, Rubenwolf P, Fuhr UTaubert M
Medline-ID vorhanden, Web of Science-ID (ISI-LOC) vorhanden

ID: 492978
Development of an 18F-Labeled Irreversible Inhibitor of Transglutaminase 2 as Radiometric Tool for Quantitative Expression Profiling in Cells and Tissues.
J Med Chem 2021; 64(6): 3462-3478; Impact Factor=n.a.; Impact Factor 2020=7.446; Typ=Journal Article;Research Support, Non-U.S. Gov't;
Wodtke R, Wodtke J, Hauser S, Laube M, Bauer D, Rothe R, Neuber C, Pietsch M, Kopka K, Pietzsch J, Löser R
Medline-ID vorhanden, Web of Science-ID (ISI-LOC) vorhanden

ID: 492598
Impact of drug formulations on kinetics and toxicity in a preclinical model of paclitaxel-induced neuropathy.
J Peripher Nerv Syst 2021; 26(2): 216-226; Impact Factor=n.a.; Impact Factor 2020=3.494; Typ=Journal Article;
Klein I, Wiesen MHJ, Albert V, Bobylev I, Joshi AR, Müller C, Lehmann HC
Medline-ID vorhanden, Web of Science-ID (ISI-LOC) vorhanden

ID: 489897
Drug-drug interactions in Neonatal Intensive Care Units: how to overcome a challenge.
Minerva Pediatr (Torino) 2021; 73(2): 188-197; Impact Factor=n.a.; Impact Factor 2020=n.a.; Typ=Journal Article;Review;
Rosen KWiesen MH, Oberthür A, Michels G, Roth B, Fietz CMüller C
Medline-ID vorhanden, Web of Science-ID (ISI-LOC) vorhanden

ID: 492970
A simulation-based module in pharmacology education reveals and addresses medical students' deficits in leading prescription talks.
Naunyn Schmiedebergs Arch Pharmacol 2021; 394(11): 2333-2341; Impact Factor=n.a.; Impact Factor 2020=3.0; Typ=Journal Article;Research Support, Non-U.S. Gov't;
Kirsch VMatthes J
Medline-ID vorhanden, Web of Science-ID (ISI-LOC) vorhanden

ID: 492973
Aspects of Medication and Patient participation-an Easy guideLine (AMPEL). A conversation guide increases patients' and physicians' satisfaction with prescription talks.
Naunyn Schmiedebergs Arch Pharmacol 2021; 394(8): 1757-1767; Impact Factor=n.a.; Impact Factor 2020=3.0; Typ=Journal Article;
Kirsch VMatthes J
Medline-ID vorhanden, Web of Science-ID (ISI-LOC) vorhanden

ID: 492979
Increased patient and physician satisfaction in guide-based prescription talks (AMPEL: Aspects of Medication and Patient participation - an Easy guideLine)
Naunyn Schmiedebergs Arch Pharmacol 2021; 394 Suppl 1(SUPPL 1): S26-S26; Impact Factor=n.a.; Impact Factor 2020=3.0; Typ=Meeting Abstract;
Kirsch VMatthes J
Medline-ID fehlt, Web of Science-ID (ISI-LOC) vorhanden

ID: 492980
We need to talk. An approach to teaching students how to conduct a prescription conversation
Naunyn Schmiedebergs Arch Pharmacol 2021; 394 Suppl 1(SUPPL 1): S41-S41; Impact Factor=n.a.; Impact Factor 2020=3.0; Typ=Meeting Abstract;
Kirsch VMatthes J
Medline-ID fehlt, Web of Science-ID (ISI-LOC) vorhanden

ID: 420463
The relation between tau pathology and granulovacuolar degeneration of neurons.
Neurobiol Dis 2021; 147(): ; Impact Factor=n.a.; Impact Factor 2020=5.996; Typ=Journal Article;
Puladi B, Dinekov M, Arzberger T, Taubert M, Köhler C
Medline-ID vorhanden, Web of Science-ID (ISI-LOC) vorhanden

ID: 492967
Scalable Synthesis of N,N ' Di(2,3-dihydroxy-propyl)-1,4-naphthalenedipropanamide and Its 1,4-Endoperoxide as a Singlet Oxygen-Releasing Molecule
Org. Process Res. Dev. 2021; 25(12): 2747-2753; Impact Factor=n.a.; Impact Factor 2020=3.317; Typ=Article;
Gemki M, Taspinar O, Adler A, Griesbeck AG, Gruendemann D, Schmalz HG
Medline-ID fehlt, Web of Science-ID (ISI-LOC) vorhanden

ID: 473945
Advancement of pharmacokinetic models of iohexol in patients aged 70 years or older with impaired kidney function.
Sci Rep 2021; 11(1): ; Impact Factor=n.a.; Impact Factor 2020=4.379; Typ=Journal Article;
Taubert M, Schaeffner E, Martus P, van der Giet M, Fuhr U, Lösment A, Ebert N
Medline-ID vorhanden, Web of Science-ID (ISI-LOC) vorhanden

ID: 492968
The effect of structured aerobic exercise on adherence, body mass index, hemoglobin A1c, and quality of life in type 1 and type 2 diabetes mellitus
Transl Sports Med 2021; 4(6): 826-836; Impact Factor=n.a.; Impact Factor 2020=n.a.; Typ=Article;
Golka M, Spiller M, Schmidt N, Turnowsky A, Grauduszus M, Matthes J, Joisten C
Medline-ID fehlt, Web of Science-ID (ISI-LOC) vorhanden

2020

Protective effects of 4-Aminopyridine in experimental optic neuritis and multiple sclerosis
Dietrich M, Koska V, Hecker C, Göttle P, Hilla AM, HeskampA, Lepka K, Issberner A, Hallenberger A, Baksmeier C, Steckel J, Balk L, Knier B, Korn T, Havla J, MartÌnez-Lapiscina EH, Sol·N, Manogaran P, Olbert ED, Schippling S, Cruz-Herranz A, Yiu H, Button J, Gonzalez Caldito N,  von Gall C, Mausberg AK, Settner M, Zimmerman H, Paul F, Brandt AU,  K¸ry P,  Goebels N, Aktas O, Berndt C,  Saidha S, Green AJ, Calabresi PA, Fischer D, Hartung HP, Albrecht P (2020)
Brain; 143(4):1127-1142. doi: 10.1093/brain/awaa062

Advances in chemistry and bioactivity of parthenolide
Freund RRA, Gobrecht P, Fischer D and Arndt HD (2020)
Nat.Prod.Rep.; 10.1039/c9np00049f

ID: 383684
Inhibition of EIF-5A prevents apoptosis in human cardiomyocytes after malaria infection.
Amino Acids 2020; 52(5): 693-710; Impact Factor=3.52; Impact Factor 2020=3.52; Typ=Journal Article;
Kaiser A, Heiss K, Mueller AK, Fimmers R, Matthes J, Njuguna JT
Medline-ID vorhanden, Web of Science-ID (ISI-LOC) vorhanden

ID: 383688
Solution-phase synthesis of the fluorogenic TGase 2 acyl donor Z-Glu(HMC)-Gly-OH and its use for inhibitor and amine substrate characterisation.
Anal Biochem 2020; 595(): ; Impact Factor=3.365; Impact Factor 2020=3.365; Typ=Journal Article;
Wodtke R, Pietsch M, Löser R
Medline-ID vorhanden, Web of Science-ID (ISI-LOC) vorhanden

ID: 383680
Antifungal prophylaxis and novel drugs in acute myeloid leukemia: the midostaurin and posaconazole dilemma.
Ann Hematol 2020; 99(7): 1429-1440; Impact Factor=3.673; Impact Factor 2020=3.673; Typ=Journal Article;Review;
Stemler J, Koehler P, Maurer C, Müller C, Cornely OA
Medline-ID vorhanden, Web of Science-ID (ISI-LOC) vorhanden

ID: 383676
Transporter tandems: precise tools for normalizing active transporter in the plasma membrane.
Biochem J 2020; 477(21): 4191-4206; Impact Factor=3.857; Impact Factor 2020=3.857; Typ=Journal Article;
Tschirka JBach MKisis I, Lemmen J, Gnoth MJ, Gründemann D
Medline-ID vorhanden, Web of Science-ID (ISI-LOC) vorhanden

ID: 383691
Unexpected CK2β-antagonistic functionality of bisubstrate inhibitors targeting protein kinase CK2.
Bioorg Chem 2020; 96(): ; Impact Factor=5.275; Impact Factor 2020=5.275; Typ=Journal Article;Research Support, Non-U.S. Gov't;
Pietsch M, Viht K, Schnitzler A, Ekambaram R, Steinkrüger M, Enkvist E, Nienberg C, Nickelsen A, Lauwers M, Jose J, Uri A, Niefind K
Medline-ID vorhanden, Web of Science-ID (ISI-LOC) vorhanden

ID: 383695
ω-Quinazolinonylalkyl aryl ureas as reversible inhibitors of monoacylglycerol lipase.
Bioorg Chem 2020; 94(): ; Impact Factor=5.275; Impact Factor 2020=5.275; Typ=Journal Article;Research Support, Non-U.S. Gov't;
Dato FM, Neudörfl JM, Gütschow M, Goldfuss B, Pietsch M
Medline-ID vorhanden, Web of Science-ID (ISI-LOC) vorhanden

ID: 383689
Prediction of exposure-driven myelotoxicity of continuous infusion 5-fluorouracil by a semi-physiological pharmacokinetic-pharmacodynamic model in gastrointestinal cancer patients.
Cancer Chemother Pharmacol 2020; 85(4): 711-722; Impact Factor=3.333; Impact Factor 2020=3.333; Typ=Journal Article;Research Support, Non-U.S. Gov't;
Arshad UPloylearmsaeng SA, Karlsson MO, Doroshyenko OLanger DSchömig E, Kunze S, Güner SA, Skripnichenko R, Ullah S, Jaehde U, Fuhr U, Jetter A, Taubert M
Medline-ID vorhanden, Web of Science-ID (ISI-LOC) vorhanden

ID: 248556
Sorafenib and everolimus in patients with advanced solid tumors and KRAS-mutated NSCLC: A phase I trial with early pharmacodynamic FDG-PET assessment.
Cancer Med 2020; 9(14): 4991-5007; Impact Factor=4.452; Impact Factor 2020=4.452; Typ=Journal Article;
Nogova L, Mattonet C, Scheffler M, Taubert M, Gardizi M, Sos ML, Michels S, Fischer RN, Limburg M, Abdulla DSY, Persigehl T, Kobe C, Merkelbach-Bruse S, Franklin J, Backes H, Schnell R, Behringer D, Kaminsky B, Eichstaedt M, Stelzer C, Kinzig M, Sörgel F, Tian Y, Junge LSuleiman AAFrechen SRokitta D, Ouyang D, Fuhr U, Buettner R, Wolf J
Medline-ID vorhanden, Web of Science-ID (ISI-LOC) vorhanden

ID: 383686
Synthesis and SAR of Tetracyclic Inhibitors of Protein Kinase CK2 Derived from Furocarbazole W16.
ChemMedChem 2020; 15(10): 871-881; Impact Factor=3.466; Impact Factor 2020=3.466; Typ=Journal Article;Research Support, Non-U.S. Gov't;
Kröger L, Daniliuc CG, Ensan D, Borgert S, Nienberg C, Lauwers MSteinkrüger M, Jose J, Pietsch M, Wünsch B
Medline-ID vorhanden, Web of Science-ID (ISI-LOC) vorhanden

ID: 383682
A Physiologically Based Pharmacokinetic Model of Voriconazole Integrating Time-Dependent Inhibition of CYP3A4, Genetic Polymorphisms of CYP2C19 and Predictions of Drug-Drug Interactions.
Clin Pharmacokinet 2020; 59(6): 781-808; Impact Factor=6.447; Impact Factor 2020=6.447; Typ=Journal Article;Research Support, Non-U.S. Gov't;
Li X, Frechen S, Moj D, Lehr T, Taubert MHsin CH, Mikus G, Neuvonen PJ, Olkkola KT, Saari TI, Fuhr U
Medline-ID vorhanden, Web of Science-ID (ISI-LOC) vorhanden

ID: 383687
Frequency and Types of Pathological Upper Gastrointestinal Endoscopy Findings in Clinically Healthy Individuals.
Drugs R D 2020; 20(2): 115-124; Impact Factor=2.594; Impact Factor 2020=2.594; Typ=Clinical Trial;Journal Article;
Scheidl E, Benz C, Loeff P, Groneck V, König A, Schulte-Fischedick A, Lück H, Fuhr U
Medline-ID vorhanden, Web of Science-ID (ISI-LOC) vorhanden

ID: 384910
Circuits that encode and guide alcohol-associated preference.
Elife 2020; 9(): ; Impact Factor=8.14; Impact Factor 2020=8.14; Typ=Journal Article;Research Support, Non-U.S. Gov't;Research Support, N.I.H., Extramural;
Scaplen KM, Talay M, Nunez KM, Salamon S, Waterman AG, Gang S, Song SL, Barnea G, Kaun KR
Medline-ID vorhanden, Web of Science-ID (ISI-LOC) vorhanden

ID: 383679
The parent drugs chloroquine and hydroxychloroquine do not inhibit human CYP3A activity in vitro.
Eur J Clin Pharmacol 2020; 76(10): 1481-1482; Impact Factor=2.953; Impact Factor 2020=2.953; Typ=Letter;
Li X, Höhl R, Sörgel F, Fuhr U
Medline-ID vorhanden, Web of Science-ID (ISI-LOC) vorhanden

ID: 383677
Distinct 3-disulfide-bonded isomers of tridegin differentially inhibit coagulation factor XIIIa: The influence of structural stability on bioactivity.
Eur J Med Chem 2020; 201(): ; Impact Factor=6.514; Impact Factor 2020=6.514; Typ=Journal Article;
Bäuml CA, Paul George AA, Schmitz T, Sommerfeld PPietsch M, Podsiadlowski L, Steinmetzer T, Biswas A, Imhof D
Medline-ID vorhanden, Web of Science-ID (ISI-LOC) vorhanden

ID: 314753
Extraocular Muscle Reveals Selective Vulnerability of Type IIB Fibers to Respiratory Chain Defects Induced by Mitochondrial DNA Alterations.
Invest Ophthalmol Vis Sci 2020; 61(12): ; Impact Factor=4.799; Impact Factor 2020=4.799; Typ=Journal Article;
Oexner RR, Pla-Martín D, Paß T, Wiesen MHJ, Zentis P, Schauss A, Baris OR, Kimoloi S, Wiesner RJ
Medline-ID vorhanden, Web of Science-ID (ISI-LOC) vorhanden

ID: 426552
Reporting the details of consent procedures in clinical trials.
J Clin Epidemiol 2020; 117(): 150-151; Impact Factor=6.437; Impact Factor 2020=6.437; Typ=Letter;Comment;
Dal Ré R, Solberg B, Fuhr U, Eriksson S
Medline-ID vorhanden, Web of Science-ID (ISI-LOC) vorhanden

ID: 383683
A Novel Study Design Using Continuous Intravenous and Intraduodenal Infusions of Midazolam and Voriconazole for Mechanistic Quantitative Assessment of Hepatic and Intestinal CYP3A Inhibition.
J Clin Pharmacol 2020; 60(9): 1237-1253; Impact Factor=3.126; Impact Factor 2020=3.126; Typ=Journal Article;
Li XJunge LTaubert Mvon Georg ADahlinger DStarke CFrechen S, Stelzer C, Kinzig M, Sörgel F, Jaehde U, Töx U, Goeser T, Fuhr U
Medline-ID vorhanden, Web of Science-ID (ISI-LOC) vorhanden

ID: 416976
The higher the better? Defining the optimal beta-lactam target for critically ill patients to reach infection resolution and improve outcome.
J Intensive Care 2020; 8(1): ; Impact Factor=3.953; Impact Factor 2020=3.953; Typ=Journal Article;
Scharf C, Liebchen U, Paal M, Taubert M, Vogeser M, Irlbeck M, Zoller M, Schroeder I
Medline-ID vorhanden, Web of Science-ID (ISI-LOC) vorhanden

ID: 383685
Structure-affinity relationships of estrogen derivatives to ER alpha as precursors for radiolabeling in endoradiotherapy of ER-positive mammary carcinomas
J Nucl Med 2020; 61 Suppl 1(): ; Impact Factor=10.057; Impact Factor 2020=10.057; Typ=Meeting Abstract;
Schomaecker K, Marmann V, Pietsch M, Kirsch S, Jaschinski M, Fischer T, Drzezga A
Medline-ID fehlt, Web of Science-ID (ISI-LOC) vorhanden

ID: 384949
Blended PbL: mixing Computer- and Problem -based Learning for 3rd year medical students
Naunyn Schmiedebergs Arch Pharmacol 2020; 393 Suppl 1(SUPPL 1): 46-46; Impact Factor=3.0; Impact Factor 2020=3.0; Typ=Meeting Abstract;
Matthes JServos U, Reiss B, Stosch C, Karay Y
Medline-ID fehlt, Web of Science-ID (ISI-LOC) vorhanden

ID: 383693
Haplotypes of the transporter gene ABCB1 influence apparent bioavailability, but not renal elimination of oral digoxin
Naunyn Schmiedebergs Arch Pharmacol 2020; 393 Suppl 1(SUPPL 1): 78-78; Impact Factor=3.0; Impact Factor 2020=3.0; Typ=Meeting Abstract;
Hsin CHStoffel MGazzaz M, Schaeffeler E, Schwab M, Li XFuhr UTaubert M
Medline-ID fehlt, Web of Science-ID (ISI-LOC) vorhanden

ID: 383694
Simplification and validation of a three-compartment model of iohexol to estimate plasma clearance in patients with impaired kidney function
Naunyn Schmiedebergs Arch Pharmacol 2020; 393 Suppl 1(SUPPL 1): 79-79; Impact Factor=3.0; Impact Factor 2020=3.0; Typ=Meeting Abstract;
Taubert M, Ebert N, Martus P, van der Giet M, Fuhr U, Schaeffner E
Medline-ID fehlt, Web of Science-ID (ISI-LOC) vorhanden

ID: 383692
Autism-associated mutations in the CaVβ2 calcium-channel subunit increase Ba2+-currents and lead to differential modulation by the RGK-protein Gem.
Neurobiol Dis 2020; 136(): ; Impact Factor=5.996; Impact Factor 2020=5.996; Typ=Journal Article;Research Support, Non-U.S. Gov't;
Despang PSalamon SBreitenkamp AFKuzmenkina EHerzig SMatthes J
Medline-ID vorhanden, Web of Science-ID (ISI-LOC) vorhanden

ID: 383690
Brain Exposure to Piperacillin in Acute Hemorrhagic Stroke Patients Assessed by Cerebral Microdialysis and Population Pharmacokinetics.
Neurocrit Care 2020; 33(3): 740-748; Impact Factor=3.21; Impact Factor 2020=3.21; Typ=Journal Article;
Ullah S, Beer R, Fuhr UTaubert M, Zeitlinger M, Kratzer A, Dorn C, Arshad U, Kofler M, Helbok R
Medline-ID vorhanden, Web of Science-ID (ISI-LOC) vorhanden

ID: 383543
Combinations of common SNPs of the transporter gene ABCB1 influence apparent bioavailability, but not renal elimination of oral digoxin.
Sci Rep 2020; 10(1): ; Impact Factor=4.379; Impact Factor 2020=4.379; Typ=Journal Article;Research Support, Non-U.S. Gov't;
Hsin CHStoffel MSGazzaz M, Schaeffeler E, Schwab M, Fuhr UTaubert M
Medline-ID vorhanden, Web of Science-ID (ISI-LOC) vorhanden

ID: 248553
Pharmacodynamic Monitoring of Mycophenolic Acid Therapy: Improved Liquid Chromatography-Tandem Mass Spectrometry Method for Measuring Inosin-5 -Monophosphate Dehydrogenase Activity
Ther Drug Monit 2020; 42(2): 282-288; Impact Factor=3.681; Impact Factor 2020=3.681; Typ=
Weissbarth GWiesen MHJFietz C, Streichert T, Ehren R, Weber LT, Muller C
Medline-ID vorhanden, Web of Science-ID (ISI-LOC) vorhanden

2019

Synthesis and biological profiling of parthenolide ether analogs
Freund RRA, Gobrecht P, Moser P, Fischer D and  Arndt HD (2019)
Org. and biomol. Chem; doi: 10.1039/c9ob02166c

Monitoring retinal changes with optical coherence tomography predicts neuronal loss in experimental autoimmune encephalomyelitis
Cruz-Herranz A, Dietrich M, Hilla AM, Yiu HH, Levin MH, Hecker C, Issberner A; Hallenberger A, Christian Cordano C, Lehmann-Horn K, Balk LJ, Aktas O, Ingwersen J, von Gall C, Hartung HP, Zamvil SS, Fischer D, Albrecht P, Green AJ (2019)
Journal of Inflammation, 6(1):203.doi: 10.1186/s12974-019-1583-4.

Stereoselective total synthesis of parthenolides indicates target selectivity for tubulin carboxypeptidase activity
Freund RRA, Gobrecht P, Rao Z, Schlosser R, Görls H, Werz O, Fischer D and Arndt AD (2019)
Chemical Science 10(31):7358-7364

GSK3/CRMP2 signaling confers PTEN knockout mediated axonal regeneration
Leibinger M, Hilla A, Andreadaki A and Fischer D (2019)
Communications Biology 2:318

The Role of Microtubule Detyrosination in Axon Regeneration (2019)
Gobrecht P,  Terheyden-Keighley D, Fischer D
Biomedical Journal of Scientific & Technical Research 17 (1), 12447-12449

Human retinal ganglion cell axon regeneration by recapitulating developmental mechanisms: effects of recruitment of the mTOR pathway (2019)
Teotia P, Van Hook MJ , Fischer D,  Ahmad I
Development 146 (13), dev178012

The role of muscle LIM protein in the nervous system (2019)
Terheyden-Keighley D, Fischer D
Neural Regeneration Research 14 (11), 1907

Muscle LIM Protein is expressed in the injured adult CNS and promotes Axon Regeneration
Levin E, Leibinger M, Gobrecht P, Hilla AM, Andreadaki A and, Fischer D (2019)
Cell Reports, 26(4):1021-1032.e6

Using optical coherence tomography and optokinetic response as structural and functional visual system readouts in mice and rats
Dietrich M, Hecker C, Hilla A, Cruz-Herranz A, Hartung HP, Fischer D, Green A, Albrecht P (2019)
Journal of Visualized Experiments, J. Vis. Exp. (143), e58571

ID: 248481
Chromenones as Multineurotargeting Inhibitors of Human Enzymes.
ACS Omega 2019; 4(26): 22161-22168; Impact Factor=2.87; Impact Factor 2020=3.512; Typ=Journal Article;
Lemke C, Christmann J, Yin J, Alonso JM, Serrano E, Chioua M, Ismaili L, Martínez-Grau MA, Beadle CD, Vetman T, Dato FM, Bartz U, Elsinghorst PW, Pietsch M, Müller CE, Iriepa I, Wille T, Marco-Contelles J, Gütschow M
Medline-ID vorhanden, Web of Science-ID (ISI-LOC) vorhanden

ID: 247931
AMD-Associated HTRA1 Variants Do Not Influence TGF-? Signaling in Microglia.
Adv Exp Med Biol 2019; 1185(): 3-7; Impact Factor=2.45; Impact Factor 2020=2.622; Typ=Journal Article;
Akhtar-Schaefer I, Reuten R, Koch M, Pietsch M, Langmann T
Medline-ID vorhanden, Web of Science-ID (ISI-LOC) vorhanden

ID: 384277
Total Synthesis and Functional Characterization of Selenoneine.
Angew Chem Int Ed Engl 2019; 58(42): 15026-15030; Impact Factor=12.959; Impact Factor 2020=15.336; Typ=Journal Article;Research Support, Non-U.S. Gov't;
Lim D, Gründemann D, Seebeck FP
Medline-ID vorhanden, Web of Science-ID (ISI-LOC) vorhanden

ID: 246694
Assessment of Pharmacokinetic Drug-Drug Interactions in Humans: In Vivo Probe Substrates for Drug Metabolism and Drug Transport Revisited.
Annu Rev Pharmacol Toxicol 2019; 59(): 507-536; Impact Factor=11.25; Impact Factor 2020=13.82; Typ=Journal Article;
Fuhr U, Hsin CH, Li X, Jabrane W, Sörgel F
Medline-ID vorhanden, Web of Science-ID (ISI-LOC) vorhanden

ID: 246677
Low risk pragmatic trials do not always require participants informed consent
BMJ-British Medical Journal 2019; 364(): l1092-; Impact Factor=30.223; Impact Factor 2020=n.a.; Typ=
Dal-Re Rafael, Avendano-Sola Cristina, Bloechl-Daum Brigitte, de Boer Anthonius, Eriksson Stefan, Fuhr Uwe, Holm Soren, James StefanK, Mentz RobertJ, Perucca Emilio, Rosendaal FritsR, Treweek Shaun
Medline-ID vorhanden, Web of Science-ID (ISI-LOC) vorhanden

ID: 246693
Single-Channel Resolution of the Interaction between C-Terminal Ca1.3 Isoforms and Calmodulin.
Biophys J 2019; 116(5): 836-846; Impact Factor=3.854; Impact Factor 2020=4.033; Typ=Journal Article;Research Support, Non-U.S. Gov't;
Kuzmenkina E, Novikova E, Jangsangthong W, Matthes J, Herzig S
Medline-ID vorhanden, Web of Science-ID (ISI-LOC) vorhanden

ID: 246692
Design of CK2?-Mimicking Peptides as Tools To Study the CK2?/CK2? Interaction in Cancer Cells.
ChemMedChem 2019; 14(8): 833-841; Impact Factor=3.124; Impact Factor 2020=3.466; Typ=Journal Article;
Lindenblatt D, Horn M, Götz C, Niefind K, Neundorf I, Pietsch M
Medline-ID vorhanden, Web of Science-ID (ISI-LOC) vorhanden

ID: 208420
A Clinical Drug-Drug Interaction Study Assessing a Novel Drug Transporter Phenotyping Cocktail With Adefovir, Sitagliptin, Metformin, Pitavastatin, and Digoxin.
Clin Pharmacol Ther 2019; 106(6): 1398-1407; Impact Factor=6.565; Impact Factor 2020=6.875; Typ=Journal Article;
Trueck C, Hsin CH, Scherf-Clavel O, Schaeffeler E, Lenssen R, Gazzaz M, Gersie M, Taubert M, Quasdorff M, Schwab M, Kinzig M, Sörgel F, Stoffel MS, Fuhr U
Medline-ID vorhanden, Web of Science-ID (ISI-LOC) vorhanden

ID: 246691
Response to "Impact of Acute Alcohol Exposure on P-Glycoprotein Function at the Blood-Brain Barrier Assessed Using C-Metoclopramide PET Imaging".
Clin Pharmacol Ther 2019; 105(4): 814; Impact Factor=6.565; Impact Factor 2020=6.875; Typ=Letter;
Hsin CH, Fuhr U, Trueck C
Medline-ID vorhanden, Web of Science-ID (ISI-LOC) vorhanden

ID: 246678
11 beta-Ethylestradiol-PEG-DOTA: A novel highly affine estrogen a receptor ligand for radio-metalation
Eur J Nucl Med Mol Imaging 2019; 46 1(SUPPL 1): S753-S753; Impact Factor=7.081; Impact Factor 2020=9.236; Typ=Meeting Abstract;
Braun F, Munoz S, Marmann V, Fischer T, Endepols H, Pietsch M, von Brandenstein M, Drzezga A, Schomaecker K
Medline-ID fehlt, Web of Science-ID (ISI-LOC) vorhanden

ID: 246679
EPI-PEG-DOTA: Novel androgen receptor ligand as an alternative to PSMA ligands
Eur J Nucl Med Mol Imaging 2019; 46 1(SUPPL 1): S82-S82; Impact Factor=7.081; Impact Factor 2020=9.236; Typ=Meeting Abstract;
Braun F, Munoz S, Marmann V, Fischer T, Endepols H, von Brandenstein M, Pietsch M, Drzezga A, Schomaecker K
Medline-ID fehlt, Web of Science-ID (ISI-LOC) vorhanden

ID: 246690
Regeneration of ergothioneine after reaction with singlet oxygen.
Free Radic Biol Med 2019; 134(): 498-504; Impact Factor=6.17; Impact Factor 2020=7.376; Typ=Journal Article;
Oumari M, Goldfuss B, Stoffels C, Schmalz HG, Gründemann D
Medline-ID vorhanden, Web of Science-ID (ISI-LOC) vorhanden

ID: 246816
Integrative Metabolomic and Metallomic Analysis in a Case-Control Cohort With Parkinson's Disease.
Front Aging Neurosci 2019; 11(): 331; Impact Factor=4.362; Impact Factor 2020=5.75; Typ=Journal Article;
Lucio M, Willkommen D, Schroeter M, Sigaroudi A, Schmitt-Kopplin P, Michalke B
Medline-ID vorhanden, Web of Science-ID (ISI-LOC) vorhanden

ID: 246689
A Single Dose of Baicalin Has No Clinically Significant Effect on the Pharmacokinetics of Cyclosporine A in Healthy Chinese Volunteers.
Front Pharmacol 2019; 10(): 518; Impact Factor=4.225; Impact Factor 2020=5.81; Typ=Journal Article;
Liu R, Li X, Wei J, Liu S, Chang Y, Zhang J, Zhang J, Zhang X, Fuhr U, Taubert M, Tian X
Medline-ID vorhanden, Web of Science-ID (ISI-LOC) vorhanden

ID: 246688
"Hopefully, I will never forget that again" - sensitizing medical students for drug safety by working on cases and simulating doctor-patient communication.
GMS J. Med. Educ. 2019; 36(2): Doc17; Impact Factor=n.a.; Impact Factor 2020=n.a.; Typ=Journal Article;Research Support, Non-U.S. Gov't;
Kirsch V, Johannsen W, Thrien C, Herzig S, Matthes J
Medline-ID vorhanden, Web of Science-ID (ISI-LOC) vorhanden

ID: 155932
Ciprofloxacin in critically ill subjects: considering hepatic function, age and sex to choose the optimal dose.
J Antimicrob Chemother 2019; 74(3): 682-690; Impact Factor=5.439; Impact Factor 2020=5.79; Typ=Journal Article;
Li X, Zoller M, Fuhr U, Huseyn-Zada M, Maier B, Vogeser M, Zander J, Taubert M
Medline-ID vorhanden, Web of Science-ID (ISI-LOC) vorhanden

ID: 248480
Plasma exposures following posaconazole delayed-release tablets in immunocompromised children and adolescents.
J Antimicrob Chemother 2019; 74(12): 3573-3578; Impact Factor=5.439; Impact Factor 2020=5.79; Typ=Journal Article;
Tragiannidis A, Herbrüggen H, Ahlmann M, Vasileiou E, Gastine S, Thorer H, Fröhlich B, Müller C, Groll AH
Medline-ID vorhanden, Web of Science-ID (ISI-LOC) vorhanden

ID: 246687
Quantification of adefovir and pitavastatin in human plasma and urine by LC-MS/MS: A useful tool for drug-drug interaction studies.
J Chromatogr B Analyt Technol Biomed Life Sci 2019; 1125(): 121718; Impact Factor=3.004; Impact Factor 2020=3.205; Typ=Journal Article;
Scherf-Clavel O, Kinzig M, Stoffel MS, Fuhr U, Sörgel F
Medline-ID vorhanden, Web of Science-ID (ISI-LOC) vorhanden

ID: 246686
A HILIC-MS/MS assay for the quantification of metformin and sitagliptin in human plasma and urine: A tool for studying drug transporter perturbation.
J Pharm Biomed Anal 2019; 175(): 112754; Impact Factor=3.209; Impact Factor 2020=3.935; Typ=Journal Article;
Scherf-Clavel O, Kinzig M, Stoffel MS, Fuhr U, Sörgel F
Medline-ID vorhanden, Web of Science-ID (ISI-LOC) vorhanden

ID: 245595
Reliable and easy-to-use LC-MS/MS-method for simultaneous determination of the antihypertensives metoprolol, amlodipine, canrenone and hydrochlorothiazide in patients with therapy-refractory arterial hypertension.
J Pharm Biomed Anal 2019; 164(): 373-381; Impact Factor=3.209; Impact Factor 2020=3.935; Typ=Journal Article;
Johannsen JO, Reuter H, Hoffmann F, Blaich C, Wiesen MHJ, Streichert T, Müller C
Medline-ID vorhanden, Web of Science-ID (ISI-LOC) vorhanden

ID: 246722
Development of visual predictive checks accounting for multimodal parameter distributions in mixture models.
J Pharmacokinet Pharmacodyn 2019; 46(3): 241-250; Impact Factor=2.461; Impact Factor 2020=n.a.; Typ=Journal Article;Research Support, Non-U.S. Gov't;
Arshad U, Chasseloup E, Nordgren R, Karlsson MO
Medline-ID vorhanden, Web of Science-ID (ISI-LOC) vorhanden

ID: 246684
A population pharmacokinetic model of intravenous telavancin in healthy individuals to assess tissue exposure.
Naunyn Schmiedebergs Arch Pharmacol 2019; 392(9): 1097-1106; Impact Factor=2.05; Impact Factor 2020=3.0; Typ=Journal Article;
Ullah S, Matzneller P, Zeitlinger M, Fuhr U, Taubert M
Medline-ID vorhanden, Web of Science-ID (ISI-LOC) vorhanden

ID: 246685
Development of perceived pharmacological deficits of medical students and alumni supports claim for continuous and more application-oriented education.
Naunyn Schmiedebergs Arch Pharmacol 2019; 392(1): 29-36; Impact Factor=2.05; Impact Factor 2020=3.0; Typ=Journal Article;Research Support, Non-U.S. Gov't;
Johannsen W, Frings B, Herzig S, Matthes J
Medline-ID vorhanden, Web of Science-ID (ISI-LOC) vorhanden

ID: 248483
Influence of EF-hand phosphorylation on biophysical gating properties of Ca(V)1.3 voltage-gated calcium channels
Naunyn Schmiedebergs Arch Pharmacol 2019; 392 1(): S34-S34; Impact Factor=2.05; Impact Factor 2020=3.0; Typ=Meeting Abstract;
Salamon S, Herzig S, Kuzmenkina E, Matthes J
Medline-ID fehlt, Web of Science-ID (ISI-LOC) vorhanden

ID: 246680
Naunyn Schmiedebergs Arch Pharmacol 2019; 392 1(): S83-S83; Impact Factor=2.05; Impact Factor 2020=3.0; Typ=Meeting Abstract;
Matthes J, Servos U, Karay Y, Reiss B, Stosch C
Medline-ID fehlt, Web of Science-ID (ISI-LOC) vorhanden

ID: 208433
Pharmacogenomics education in medical and pharmacy schools: conclusions of a global survey.
Pharmacogenomics 2019; 20(9): 643-657; Impact Factor=2.339; Impact Factor 2020=2.533; Typ=Journal Article;Research Support, Non-U.S. Gov't;
Karas Kuželički N, Prodan Žitnik I, Gurwitz D, Llerena A, Cascorbi I, Siest S, Simmaco M, Ansari M, Pazzagli M, Di Resta C, Brandslund I, Schwab M, Vermeersch P, Lunshof JE, Dedoussis G, Flordellis CS, Fuhr U, Stingl JC, van Schaik RH, Manolopoulos VG, Marc J, Pharmacogenomics Education Working Group (PGxEWG) , European Society of Pharmacogenomics and Personalized Therapy (ESPT)
Medline-ID vorhanden, Web of Science-ID (ISI-LOC) vorhanden

ID: 246683
Direct, gabapentin-insensitive interaction of a soluble form of the calcium channel subunit ??-1 with thrombospondin-4.
Sci Rep 2019; 9(1): 16272; Impact Factor=3.998; Impact Factor 2020=4.379; Typ=Journal Article;
El-Awaad E, Pryymachuk G, Fried C, Matthes J, Isensee J, Hucho T, Neiss WF, Paulsson M, Herzig S, Zaucke F, Pietsch M
Medline-ID vorhanden, Web of Science-ID (ISI-LOC) vorhanden

ID: 246681
Generation and Validation of a Limited Sampling Strategy to Monitor Mycophenolic Acid Exposure in Children With Nephrotic Syndrome.
Ther Drug Monit 2019; 41(6): 696-702; Impact Factor=2.073; Impact Factor 2020=3.681; Typ=Journal Article;
Benz MR, Ehren R, Kleinert D, Müller C, Gellermann J, Fehrenbach H, Schmidt H, Weber LT
Medline-ID vorhanden, Web of Science-ID (ISI-LOC) vorhanden

ID: 246682
Interlaboratory Analysis of Isavuconazole Plasma Concentration Assays Among European Laboratories.
Ther Drug Monit 2019; 41(5): 657-664; Impact Factor=2.073; Impact Factor 2020=3.681; Typ=Journal Article;Research Support, Non-U.S. Gov't;
Pea F, Krause R, Müller C, Hennart B, Richardson M, Meinitzer A, Wiesen MHJ, Wiktorowicz T, Spickermann J, Henriksen AS
Medline-ID vorhanden, Web of Science-ID (ISI-LOC) vorhanden

2018

Effects of Quinine, Quinidine and Chloroquine on Human Muscle Nicotinic Acetylcholine Receptors.
Gisselmann G, Alisch D, Welbers-Joop B, Hatt H (2018)
Front Pharmacol. 9:1339

Studying the Role of Microglia in Neurodegeneration and Axonal Regeneration in the murine Visual System
Hilla A and Fischer D (2018)
Bio-protocol 8(16): e2979

Early alpha-lipoic acid therapy protects from degeneration of the inner retinal layers and vision loss in an experimental autoimmune encephalomyelitis-optic neuritis model
Dietrich M, Helling N, Hilla A, Heskamp A, Issberner A, Hildebrandt T, Kohne Z, Küry P, Berndt C, Aktas O, Fischer D, Hartung HP, Albrecht P (2018)
Journal of Neuroinflammation; 15(1): 71

ID: 243944
Crystal structure of highly glycosylated human leukocyte elastase in complex with an S2' site binding inhibitor.
Acta Crystallogr F Struct Biol Commun 2018; 74(Pt 8): 480-489; Impact Factor=1.199; Impact Factor 2020=n.a.; Typ=Journal Article;Research Support, Non-U.S. Gov't;
Hochscherf J, Pietsch M, Tieu W, Kuan K, Abell AD, Gütschow M, Niefind K
Medline-ID vorhanden, Web of Science-ID (ISI-LOC) vorhanden

ID: 243943
Characterization of fatty acid amide hydrolase activity by a fluorescence-based assay.
Anal Biochem 2018; 546(): 50-57; Impact Factor=2.507; Impact Factor 2020=3.365; Typ=Journal Article;Research Support, Non-U.S. Gov't;
Dato FM, Maaßen A, Goldfuß B, Pietsch M
Medline-ID vorhanden, Web of Science-ID (ISI-LOC) vorhanden

ID: 243580
Pharmacokinetic Modeling of Voriconazole To Develop an Alternative Dosing Regimen in Children.
Antimicrob Agents Chemother 2018; 62(1): ; Impact Factor=4.715; Impact Factor 2020=5.191; Typ=Journal Article;
Gastine S, Lehrnbecher T, Müller C, Farowski F, Bader P, Ullmann-Moskovits J, Cornely OA, Groll AH, Hempel G
Medline-ID vorhanden, Web of Science-ID (ISI-LOC) vorhanden

ID: 243957
Population Pharmacokinetics of Finafloxacin in Healthy Volunteers and Patients with Complicated Urinary Tract Infections.
Antimicrob Agents Chemother 2018; 62(4): ; Impact Factor=4.715; Impact Factor 2020=5.191; Typ=Journal Article;Research Support, Non-U.S. Gov't;
Taubert M, Lückermann M, Vente A, Dalhoff A, Fuhr U
Medline-ID vorhanden, Web of Science-ID (ISI-LOC) vorhanden

ID: 244621
Reliable and Easy-To-Use Liquid Chromatography-Tandem Mass Spectrometry Assay for Quantification of Olorofim (F901318), a Novel Antifungal Drug, in Human Plasma and Serum.
Antimicrob Agents Chemother 2018; 62(11): ; Impact Factor=4.715; Impact Factor 2020=5.191; Typ=Journal Article;
Müller CFietz C, Koehler P, Sibley G, Nforbugwe ACA, Streichert T, Wiesen MHJ
Medline-ID vorhanden, Web of Science-ID (ISI-LOC) vorhanden

ID: 245181
Alternative Splicing at N Terminus and Domain I Modulates Ca1.2 Inactivation and Surface Expression.
Biophys J 2018; 114(9): 2095-2106; Impact Factor=3.665; Impact Factor 2020=4.033; Typ=Journal Article;
Bartels P, Yu D, Huang H, Hu Z, Herzig S, Soong TW
Medline-ID vorhanden, Web of Science-ID (ISI-LOC) vorhanden

ID: 245187
?-Phthalimidoalkyl Aryl Ureas as Potent and Selective Inhibitors of Cholesterol Esterase.
ChemMedChem 2018; 13(17): 1833-1847; Impact Factor=3.016; Impact Factor 2020=3.466; Typ=Journal Article;
Dato FM, Sheikh M, Uhl RZ, Schüller AW, Steinkrüger M, Koch P, Neudörfl JM, Gütschow M, Goldfuss B, Pietsch M
Medline-ID vorhanden, Web of Science-ID (ISI-LOC) vorhanden

ID: 50412
Drinking Ethanol Has Few Acute Effects on CYP2C9, CYP2C19, NAT2, and P-Glycoprotein Activities but Somewhat Inhibits CYP1A2, CYP2D6, and Intestinal CYP3A: So What?
Clin Pharmacol Ther 2018; 104(6): 1249-1259; Impact Factor=6.336; Impact Factor 2020=6.875; Typ=Journal Article;
Gazzaz M, Kinzig M, Schaeffeler E, Jübner M, Hsin CHLi XTaubert MTrueck C, Iltgen-Breburda J, Kraus D, Queckenberg C, Stoffel M, Schwab M, Sörgel F, Fuhr U
Medline-ID vorhanden, Web of Science-ID (ISI-LOC) vorhanden

ID: 245336
Key Learning Outcomes for Clinical Pharmacology and Therapeutics Education in Europe: A Modified Delphi Study.
Clin Pharmacol Ther 2018; 104(2): 317-325; Impact Factor=6.336; Impact Factor 2020=6.875; Typ=Journal Article;
Brinkman DJ, Tichelaar J, Mokkink LB, Christiaens T, Likic R, Maciulaitis R, Costa J, Sanz EJ, Maxwell SR, Richir MC, van Agtmael MA, Education Working Group of the European Association for Clinical Pharmacology and Therapeutics (EACPT) and its affiliated Network of Teachers in Pharm
Medline-ID vorhanden, Web of Science-ID (ISI-LOC) vorhanden

ID: 245186
Pharmacokinetic Phenotyping to Predict Drug-Drug Interactions: Time to Divorce the Hybrid Concept of Simultaneous Mechanistic-Based and Exposure-Based Assessment.
Clin Pharmacol Ther 2018; 103(1): 42; Impact Factor=6.336; Impact Factor 2020=6.875; Typ=Letter;
Fuhr U
Medline-ID vorhanden, Web of Science-ID (ISI-LOC) vorhanden

ID: 245241
Substrate Selectivity Check of the Ergothioneine Transporter.
Drug Metab Dispos 2018; 46(6): 779-785; Impact Factor=3.354; Impact Factor 2020=n.a.; Typ=Journal Article;
Tschirka JKreisor MBetz JGründemann D
Medline-ID vorhanden, Web of Science-ID (ISI-LOC) vorhanden

ID: 244622
Residual rivaroxaban exposure after discontinuation of anticoagulant therapy in patients undergoing cardiac catheterization.
Eur J Clin Pharmacol 2018; 74(5): 611-618; Impact Factor=2.774; Impact Factor 2020=2.953; Typ=Journal Article;Observational Study;
Wiesen MHJBlaich CTaubert M, Jennissen V, Streichert T, Pfister R, Michels G
Medline-ID vorhanden, Web of Science-ID (ISI-LOC) vorhanden

ID: 196770
Enzyme autoinduction by mitotane supported by population pharmacokinetic modelling in a large cohort of adrenocortical carcinoma patients.
Eur J Endocrinol 2018; 179(5): 287-297; Impact Factor=5.107; Impact Factor 2020=6.664; Typ=Journal Article;
Arshad UTaubert M, Kurlbaum M, Frechen S, Herterich S, Megerle F, Hamacher S, Fassnacht M, Fuhr U, Kroiss M
Medline-ID vorhanden, Web of Science-ID (ISI-LOC) vorhanden

ID: 245242
Does teaching social and communicative competences influence dental students' attitudes towards learning communication skills? A comparison between two dental schools in Germany.
GMS J. Med. Educ. 2018; 35(2): Doc18; Impact Factor=n.a.; Impact Factor 2020=n.a.; Typ=Journal Article;
Lichtenstein NV, Haak R, Ensmann I, Hallal H, Huttenlau J, Krämer K, Krause F, Matthes J, Stosch C
Medline-ID vorhanden, Web of Science-ID (ISI-LOC) vorhanden

ID: 245166
Monitoring of sedation depth in intensive care unit by therapeutic drug monitoring? A prospective observation study of medical intensive care patients.
J Intensive Care 2018; 6(): 62; Impact Factor=n.a.; Impact Factor 2020=3.953; Typ=Journal Article;
Nies RJ, Müller C, Pfister R, Binder PS, Nosseir N, Nettersheim FS, Kuhr K, Wiesen MHJ, Kochanek M, Michels G
Medline-ID vorhanden, Web of Science-ID (ISI-LOC) vorhanden

ID: 245243
N-Acryloyllysine Piperazides as Irreversible Inhibitors of Transglutaminase 2: Synthesis, Structure-Activity Relationships, and Pharmacokinetic Profiling.
J Med Chem 2018; 61(10): 4528-4560; Impact Factor=6.054; Impact Factor 2020=7.446; Typ=Journal Article;
Wodtke R, Hauser C, Ruiz-Gómez G, Jäckel E, Bauer D, Lohse M, Wong A, Pufe J, Ludwig FA, Fischer S, Hauser S, Greif D, Pisabarro MT, Pietzsch J, Pietsch M, Löser R
Medline-ID vorhanden, Web of Science-ID (ISI-LOC) vorhanden

ID: 245293
Species fractionation in a case-control study concerning Parkinson's disease: Cu-amino acids discriminate CSF of PD from controls.
J Trace Elem Med Biol 2018; 49(): 164-170; Impact Factor=2.895; Impact Factor 2020=3.849; Typ=Journal Article;
Willkommen D, Lucio M, Schmitt-Kopplin P, Gazzaz M, Schroeter M, Sigaroudi A, Michalke B
Medline-ID vorhanden, Web of Science-ID (ISI-LOC) vorhanden

ID: 245246
A cocktail study to assess pharmacokinetic interactions of acute ethanol intake
Naunyn Schmiedebergs Arch Pharmacol 2018; 391 1(): S24-S24; Impact Factor=2.058; Impact Factor 2020=3.0; Typ=Meeting Abstract;
Trueck CGazzaz M, Kinzig M, Schaffeler E, Kinzig M, Jubner M, Hsin CHLi XTaubert M, Iltgeb-Breburda J, Kraus DQueckenberg CStoffel M, Schwab M, Sorgel F, Fuhr U
Medline-ID fehlt, Web of Science-ID (ISI-LOC) vorhanden

ID: 245248
Finally confident - Self-appraisal of pharmacological deficits by medical students and alumni
Naunyn Schmiedebergs Arch Pharmacol 2018; 391 1(): S56-S56; Impact Factor=2.058; Impact Factor 2020=3.0; Typ=Meeting Abstract;
Frings B, Johannsen W, Herzig S, Matthes J
Medline-ID fehlt, Web of Science-ID (ISI-LOC) vorhanden

ID: 245249
Functional relevance of a point mutation in an autism risk gene coding for the calcium channel subunit Cav beta 1b
Naunyn Schmiedebergs Arch Pharmacol 2018; 391 1(): S70-S70; Impact Factor=2.058; Impact Factor 2020=3.0; Typ=Meeting Abstract;
Despang P, Breitenkamp A, Salamon S, Brill M, Herzig S, Matthes J
Medline-ID fehlt, Web of Science-ID (ISI-LOC) vorhanden

ID: 245247
Lack of mutual pharmacokinetics DDIS for a novel transporter phenotyping cocktail
Naunyn Schmiedebergs Arch Pharmacol 2018; 391 1(): S44-S44; Impact Factor=2.058; Impact Factor 2020=3.0; Typ=Meeting Abstract;
Hsin CH, Kinzig M, Schaffeler E, Lenssen R, Taubert MTrueck CGazzaz MQuasdorff M, Schwab M, Sorgel F, Stoffel MFuhr U
Medline-ID fehlt, Web of Science-ID (ISI-LOC) vorhanden

ID: 245312
Metabolomic investigations in cerebrospinal fluid of Parkinson's disease.
PLoS ONE 2018; 13(12): e0208752; Impact Factor=2.776; Impact Factor 2020=3.24; Typ=Journal Article;
Willkommen D, Lucio M, Moritz F, Forcisi S, Kanawati B, Smirnov KS, Schroeter M, Sigaroudi A, Schmitt-Kopplin P, Michalke B
Medline-ID vorhanden, Web of Science-ID (ISI-LOC) vorhanden

ID: 244199
Mycophenolate mofetil following glucocorticoid treatment in Henoch-Schönlein purpura nephritis: the role of early initiation and therapeutic drug monitoring.
Pediatr Nephrol 2018; 33(4): 619-629; Impact Factor=2.816; Impact Factor 2020=3.714; Typ=Journal Article;
Hackl A, Becker JU, Körner LM, Ehren R, Habbig S, Nüsken E, Nüsken KD, Ebner K, Liebau MC, Müller C, Pohl M, Weber LT
Medline-ID vorhanden, Web of Science-ID (ISI-LOC) vorhanden

ID: 245244
Quantification of Bisoprolol and Metoprolol in Simultaneous Human Serum and Cerebrospinal Fluid Samples.
Pharmacology 2018; 101(1-2): 29-34; Impact Factor=1.615; Impact Factor 2020=2.547; Typ=Journal Article;
Sigaroudi A, Kinzig M, Wahl O, Stelzer C, Schroeter M, Fuhr U, Holzgrabe U, Sörgel F
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ID: 245245
Quantification of Hydrochlorothiazide and Ramipril/Ramiprilate in Blood Serum and Cerebrospinal Fluid: A Pharmacokinetic Assessment of Central Nervous System Adverse Effects.
Pharmacology 2018; 102(3-4): 133-137; Impact Factor=1.615; Impact Factor 2020=2.547; Typ=Journal Article;
Sigaroudi A, Kinzig M, Wahl O, Stelzer C, Schroeter M, Fuhr U, Holzgrabe U, Sörgel F
Medline-ID vorhanden, Web of Science-ID (ISI-LOC) vorhanden

ID: 245337
Anti-inflammatory and cytotoxic withanolides from Physalis minima.
Phytochemistry 2018; 155(): 164-170; Impact Factor=2.905; Impact Factor 2020=4.072; Typ=Journal Article;
Wu J, Li X, Zhao J, Wang R, Xia Z, Li X, Liu Y, Xu Q, Khan IA, Yang S
Medline-ID vorhanden, Web of Science-ID (ISI-LOC) vorhanden

ID: 51590
Using a three-compartment model improves the estimation of iohexol clearance to assess glomerular filtration rate.
Sci Rep 2018; 8(1): 17723; Impact Factor=4.011; Impact Factor 2020=4.379; Typ=Journal Article;
Taubert M, Ebert N, Martus P, van der Giet M, Fuhr U, Schaeffner E
Medline-ID vorhanden, Web of Science-ID (ISI-LOC) vorhanden

ID: 246237
Rivaroxaban plasma levels in patients admitted for bleeding events: insights from a prospective study.
Thromb J 2018; 16(): 28; Impact Factor=n.a.; Impact Factor 2020=5.5; Typ=Journal Article;
Sennesael AL, Larock AS, Douxfils J, Elens L, Stillemans G, Wiesen M, Taubert M, Dogné JM, Spinewine A, Mullier F
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2017

Optic Nerve Regeneration in Mammals: Regenerated or Spared Axons?
Fischer D, Harvey AR, Pernet V, Lemmon VP and Park KK (2017)
Exp. Neurology; 296:83-88

Boosting CNS axon regeneration by harnessing antagonistic effects of GSK3 activity
Leibinger M, Andreadaki A, Golla R, Levin E, Hilla AM, Diekmann H and Fischer D (2017)
PNAS; 201621225. doi: 10.1073/pnas.1621225114

Microglia are irrelevant for neuronal degeneration and axon regeneration after acute injury
Hilla AM, Diekmann H and Fischer D (2017)
Journal of Neuroscience; 37(25):6113-6124

Nociceptive DRG neurons express muscle lim protein upon axonal injury
Levin E, Andreadaki A, Gobrecht P, Bosse F and Fischer D (2017)
Scientific Reports; 7(1):643

ID: 242881
A fluorescence anisotropy-based assay for determining the activity of tissue transglutaminase.
Amino Acids 2017; 49(3): 567-583; Impact Factor=2.906; Impact Factor 2020=3.52; Typ=Journal Article;
Hauser C, Wodtke R, Löser R, Pietsch M
Medline-ID vorhanden, Web of Science-ID (ISI-LOC) vorhanden

ID: 242882
Pharmacokinetics of Intravenous Finafloxacin in Healthy Volunteers.
Antimicrob Agents Chemother 2017; 61(10): ; Impact Factor=4.255; Impact Factor 2020=5.191; Typ=Journal Article;
Taubert M, Chiesa J, Lückermann M, Fischer C, Dalhoff A, Fuhr U
Medline-ID vorhanden, Web of Science-ID (ISI-LOC) vorhanden

ID: 242883
A novel mode of operation of SLC22A11: Membrane insertion of estrone sulfate versus translocation of uric acid and glutamate.
Biochem Pharmacol 2017; 128(): 74-82; Impact Factor=4.235; Impact Factor 2020=5.858; Typ=Journal Article;
Skwara PSchömig EGründemann D
Medline-ID vorhanden, Web of Science-ID (ISI-LOC) vorhanden

ID: 242947
Paramagnetic micro-particles as a tool for rapid quantification of apixaban, dabigatran, edoxaban and rivaroxaban in human plasma by UHPLC-MS/MS
Clin Chem Lab Med 2017; 55(9): 1349-1359; Impact Factor=3.556; Impact Factor 2020=3.694; Typ=
Wiesena MHJBlaich C, Streichert T, Michels G, Muller C
Medline-ID vorhanden, Web of Science-ID (ISI-LOC) vorhanden

ID: 242880
Renal Metabolic Programming Is Linked to the Dynamic Regulation of a Leptin-Klf15 Axis and Akt/AMPK? Signaling in Male Offspring of Obese Dams.
Endocrinology 2017; 158(10): 3399-3415; Impact Factor=3.961; Impact Factor 2020=4.736; Typ=Journal Article;
Kasper P, Vohlen C, Dinger K, Mohr J, Hucklenbruch-Rother E, Janoschek R, Köth J, Matthes J, Appel S, Dötsch J, Alejandre Alcazar MA
Medline-ID vorhanden, Web of Science-ID (ISI-LOC) vorhanden

ID: 242884
Ergothioneine stands out from hercynine in the reaction with singlet oxygen: Resistance to glutathione and TRIS in the generation of specific products indicates high reactivity.
Free Radic Biol Med 2017; 113(): 385-394; Impact Factor=6.02; Impact Factor 2020=7.376; Typ=Journal Article;
Stoffels COumari MPerrou A, Termath A, Schlundt W, Schmalz HG, Schäfer M, Wewer V, Metzger S, Schömig EGründemann D
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ID: 243679
A multi-centre student survey on weighing disciplines in medical curricula - a pilot study.
GMS J. Med. Educ. 2017; 34(2): Doc24; Impact Factor=n.a.; Impact Factor 2020=n.a.; Typ=Journal Article;
Dafsari HS, Herzig S, Matthes J
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ID: 243685
Publication activity in medical education research: A descriptive analysis of submissions to the GMS Zeitschrift für Medizinische Ausbildung in 2007-2015.
GMS J. Med. Educ. 2017; 34(3): Doc32; Impact Factor=n.a.; Impact Factor 2020=n.a.; Typ=Journal Article;
Matthes J, Giesler M, Wagner-Menghin M, Himmelbauer M, Preusche I, Schüttpelz-Brauns K
Medline-ID vorhanden, Web of Science-ID (ISI-LOC) vorhanden

ID: 243674
The prescription talk - an approach to teach patient-physician conversation about drug prescription to medical students.
GMS J. Med. Educ. 2017; 34(2): Doc18; Impact Factor=n.a.; Impact Factor 2020=n.a.; Typ=Journal Article;
Hauser K, Koerfer A, Niehaus M, Albus C, Herzig S, Matthes J
Medline-ID vorhanden, Web of Science-ID (ISI-LOC) vorhanden

ID: 244343
Low penetration of caspofungin into cerebrospinal fluid following intravenous administration of standard doses.
Int J Antimicrob Agents 2017; 50(2): 272-275; Impact Factor=4.253; Impact Factor 2020=5.283; Typ=Journal Article;
Strenger V, Farowski F, Müller C, Hofer N, Dornbusch HJ, Sperl D, Lackner H, Benesch M, Urban C
Medline-ID vorhanden, Web of Science-ID (ISI-LOC) vorhanden

ID: 152893
Optimization of linezolid therapy in the critically ill: the effect of adjusted infusion regimens.
J Antimicrob Chemother 2017; 72(8): 2304-2310; Impact Factor=5.217; Impact Factor 2020=5.79; Typ=Journal Article;
Taubert M, Zander J, Frechen S, Scharf C, Frey L, Vogeser M, Fuhr U, Zoller M
Medline-ID vorhanden, Web of Science-ID (ISI-LOC) vorhanden

ID: 91242
Beta-adrenergic regulation of the heart expressing the Ser1700A/Thr1704A mutated Cav1.2 channel.
J Mol Cell Cardiol 2017; 111(): 10-16; Impact Factor=5.296; Impact Factor 2020=5.0; Typ=Journal Article;
Poomvanicha M, Matthes J, Domes K, Patrucco E, Angermeier E, Laugwitz KL, Schneider T, Hofmann F
Medline-ID vorhanden, Web of Science-ID (ISI-LOC) vorhanden

ID: 242885
Metformin causes a futile intestinal-hepatic cycle which increases energy expenditure and slows down development of a type 2 diabetes-like state.
Mol Metab 2017; 6(7): 737-747; Impact Factor=6.291; Impact Factor 2020=7.422; Typ=Journal Article;
Schommers P, Thurau A, Bultmann-Mellin I, Guschlbauer M, Klatt AR, Rozman J, Klingenspor M, de Angelis MH, Alber J, Gründemann D, Sterner-Kock A, Wiesner RJ
Medline-ID vorhanden, Web of Science-ID (ISI-LOC) vorhanden

ID: 243681
Loss of organic cation transporter 3 (Oct3) leads to enhanced proliferation and hepatocarcinogenesis.
Oncotarget 2017; 8(70): 115667-115680; Impact Factor=n.a.; Impact Factor 2020=n.a.; Typ=Journal Article;
Vollmar J, Lautem A, Closs E, Schuppan D, Kim YO, Grimm D, Marquardt JU, Fuchs P, Straub BK, Schad A, Gründemann D, Schattenberg JM, Gehrke N, Wörns MA, Baumgart J, Galle PR, Zimmermann T
Medline-ID vorhanden, Web of Science-ID (ISI-LOC) vorhanden

ID: 242886
Ergothioneine and related histidine derivatives in the gas phase: tautomer structures determined by IRMPD spectroscopy and theory.
Phys Chem Chem Phys 2017; 19(34): 23362-23372; Impact Factor=3.906; Impact Factor 2020=3.676; Typ=Journal Article;
Peckelsen K, Martens J, Czympiel L, Oomens J, Berden G, Gründemann D, Meijer AJHM, Schäfer M
Medline-ID vorhanden, Web of Science-ID (ISI-LOC) vorhanden

ID: 244452
Exclusion of alternative exon 33 of Ca1.2 calcium channels in heart is proarrhythmogenic.
Proc Natl Acad Sci U S A 2017; 114(21): E4288-E4295; Impact Factor=9.504; Impact Factor 2020=11.205; Typ=Journal Article;
Li G, Wang J, Liao P, Bartels P, Zhang H, Yu D, Liang MC, Poh KK, Yu CY, Jiang F, Yong TF, Wong YP, Hu Z, Huang H, Zhang G, Galupo MJ, Bian JS, Ponniah S, Trasti SL, See K, Foo R, Hoppe UC, Herzig S, Soong TW
Medline-ID vorhanden, Web of Science-ID (ISI-LOC) vorhanden

ID: 242887
Assessment of inhibitory effects on major human cytochrome P450 enzymes by spasmolytics used in the treatment of overactive bladder syndrome.
Ther Adv Urol 2017; 9(7): 163-177; Impact Factor=n.a.; Impact Factor 2020=2.357; Typ=Journal Article;
Dahlinger D, Aslan S, Pietsch M, Frechen S, Fuhr U
Medline-ID vorhanden, Web of Science-ID (ISI-LOC) vorhanden

ID: 242949
Reliable and Easy-To-Use Liquid Chromatography-Tandem Mass Spectrometry Method for Simultaneous Analysis of Fluconazole, Isavuconazole, Itraconazole, Hydroxy-Itraconazole, Posaconazole, and Voriconazole in Human Plasma and Serum
Ther Drug Monit 2017; 39(5): 505-513; Impact Factor=2.092; Impact Factor 2020=3.681; Typ=
Mueller C, Gehlen D, Blaich C, Prozeller D, Liss B, Streichert T, Wiesen MHJ
Medline-ID vorhanden, Web of Science-ID (ISI-LOC) vorhanden

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